⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167805 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL9723617 | 0.97 | — | — | |
| Maleic Acid SCHEMBL6871002 | 0.87 | TSHR (0.64) | — | |
| Fumaric Acid SCHEMBL1024373 | 0.87 | TSHR (0.64) | — | |
| Fumaric Acid SCHEMBL27092735 | 0.87 | TSHR (0.64) | — | |
| Maleic Acid SCHEMBL6052835 | 0.87 | TSHR (0.64) | — | |
| Fumaric Acid SCHEMBL713345 | 0.87 | TSHR (0.64) | — | |
| Maleic Acid SCHEMBL342490 | 0.87 | TSHR (0.64) | — | |
| Maleic Acid SCHEMBL713343 | 0.87 | TSHR (0.64) | — | |
| Fumaric Acid SCHEMBL6871005 | 0.87 | TSHR (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757770-B | 3-Phenyl-4-hexynoic acid derivatives as GPR40 agonists | 赛隆制药股份公司 | 2023-10-03 | — | — | CN | disclosed |
| US-11111206-B2 | Monomers and polymers formed thereby | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2021-09-07 | — | — | US | disclosed |
| US-20190084915-A1 | MONOMERS AND POLYMERS FORMED THEREBY | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2019-03-21 | — | — | US | disclosed |
| EP-2213666-B1 | LIGUSTRAZINE AROMATIC ACID ETHER DERIVATIVE, ITS PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION | LI JIAMING (CN) | 2012-02-15 | — | — | EP | disclosed |
| US-8012628-B2 | Polymer electrochemical device | KURARAY CO., LTD. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-7371747-B2 | Cyanoalkylamino derivatives as protease inhibitors | MERCK FROSST CANADA & CO. (CA) | 2008-05-13 | — | — | US | disclosed |
| EP-1446115-B1 | CYANOALKYLAMINO DERIVATIVES AS PROTEASE INHIBITORS | MERCK FROSST CANADA LTD (CA) | 2008-02-27 | — | — | EP | disclosed |
| US-20080014505-A1 | POLYMER ELECTROCHEMICAL DEVICE | KURARAY CO., LTD. (JP) | 2008-01-17 | — | — | US | disclosed |
| EP-1870597-A2 | Polymer electrochemical device | Kuraray Co., Ltd. (JP) | 2007-12-26 | — | — | EP | disclosed |
| EP-1446115-A4 | CYANOALKYLAMINO DERIVATIVES AS PROTEASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2005-02-02 | — | — | EP | disclosed |
| US-20050014941-A1 | Cyanoalkylamino derivatives as protease inhibitors | MERCK FROSST CANADA LTD. (CA) | 2005-01-20 | — | — | US | disclosed |
| EP-1446115-A2 | CYANOALKYLAMINO DERIVATIVES AS PROTEASE INHIBITORS | Merck Frosst Canada & Co. (CA) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003041649-A2 | CYANOALKYLAMINO DERIVATIVES AS PROTEASE INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2003-05-22 | — | — | WO | disclosed |
| US-4863926-A | ANTICOAGULANTS, HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| US-4782088-A | HYPOTENSIVE, ANTITHROMBOTIC | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| US-4778804-A | ANTICOAGULANTS, HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| US-4767768-A | ANTITHROMBIC, HYPOTENSIVE; OXIME-SUBSTITUTED | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-30 | — | — | US | disclosed |
| EP-0113106-B1 | NEW NITRO ALIPHATIC COMPOUNDS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0113106-A1 | New nitro aliphatic compounds, process for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-11 | — | — | EP | disclosed |