Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 3/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | HTR1B | P28222 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22950016 | 0.91 | TSHR (0.46) | TSHRPOLBRXRARXRBHSD17B2 | |
| SCHEMBL16615379 | 0.89 | TSHR (0.48) | TSHRPOLBRXRARXRBHSD17B2 | |
| SCHEMBL11984188 | 0.89 | TSHR (0.46) | TSHRPOLBRXRBLMNATYR | |
| SCHEMBL14981042 | 0.87 | TSHR (0.58) | TSHRPOLBHSD17B2LMNATYR | |
| SCHEMBL19901698 | 0.84 | TSHR (0.46) | TSHRPOLBRXRARXRBHSD17B2 | |
| SCHEMBL16615341 | 0.83 | POLB (0.40) | TSHRPOLBRXRARXRBHSD17B2 | |
| SCHEMBL15158563 | 0.83 | TSHR (0.50) | TSHRRXRARXRBHSD17B2LMNA | |
| SCHEMBL12018768 | 0.83 | TSHR (0.50) | TSHRPOLBRXRARXRBLMNA | |
| SCHEMBL2607267 | 0.83 | TSHR (0.50) | TSHRPOLBRXRARXRBLMNA | |
| SCHEMBL22779258 | 0.83 | TSHR (0.39) | TSHRPOLBHDAC8NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3909958-A1 | COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG Chem, Ltd. (KR) | 2021-11-17 | — | — | EP | disclosed |