Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 3/20 | 0.32 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16615344 | 0.89 | RXRB (0.38) | POLBGABRA1GABRB2HTR1DTSHR | |
| SCHEMBL19901698 | 0.84 | TSHR (0.46) | POLBGABRA1GABRB2HTR1DTSHR | |
| SCHEMBL24019348 | 0.83 | TSHR (0.42) | POLBHTR1DTSHRHTR1BRXRB | |
| SCHEMBL15158560 | 0.83 | GABRA1 (0.41) | POLBGABRA1GABRB2HTR1DTSHR | |
| SCHEMBL16615379 | 0.82 | TSHR (0.48) | POLBHTR1DTSHRHTR1BRXRB | |
| SCHEMBL6716792 | 0.81 | CYP2D6 (0.37) | POLBHTR1DTSHRHTR1BRXRB | |
| SCHEMBL1116041 | 0.80 | RAPGEF4 (0.40) | POLBHTR1DTSHRRXRBRXRA | |
| SCHEMBL15304825 | 0.80 | RAPGEF4 (0.40) | POLBHTR1DTSHRRXRBRXRA | |
| SCHEMBL12018768 | 0.79 | TSHR (0.50) | POLBGABRA1GABRB2HTR1DTSHR | |
| SCHEMBL2607267 | 0.79 | TSHR (0.50) | POLBGABRA1GABRB2HTR1DTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160218291-A1 | POLYMER AND ORGANIC LIGHT EMITTING DEVICE | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2016-07-28 | — | — | US | disclosed |
| US-20160218291-A1 | POLYMER AND ORGANIC LIGHT EMITTING DEVICE | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2016-07-28 | — | — | US | disclosed |
| WO-2015044656-A1 | POLYMER AND ORGANIC LIGHT EMITTING DEVICE | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2015-04-02 | — | — | WO | disclosed |