Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.76 |
| ▸ | MEN1 | O00255 | 8/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.76 |
| ▸ | HPGD | P15428 | 3/20 | 0.76 |
| ▸ | PPARG | P37231 | 1/20 | 0.76 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24029048 | 0.86 | KMT2A (1.00) | KMT2AMEN1ALDH1A1MAPK1HPGD | |
| SCHEMBL24019575 | 0.86 | ALDH1A1 (1.00) | KMT2AMEN1ALDH1A1MAPK1HPGD | |
| SCHEMBL24019599 | 0.84 | HPGD (1.00) | KMT2AMEN1ALDH1A1MAPK1HPGD | |
| SCHEMBL24209682 | 0.78 | MAPT (0.71) | KMT2AMEN1ALDH1A1MAPK1HPGD | |
| SCHEMBL24209699 | 0.78 | HPGD (0.79) | KMT2AMEN1ALDH1A1MAPK1HPGD | |
| SCHEMBL24019594 | 0.77 | TP53 (0.72) | KMT2AMEN1ALDH1A1MAPK1HPGD | |
| SCHEMBL21951986 | 0.76 | MAPT (0.71) | KMT2AMEN1ALDH1A1MAPK1HPGD | |
| SCHEMBL24019574 | 0.76 | HPGD (0.80) | KMT2AMEN1ALDH1A1MAPK1HPGD | |
| SCHEMBL16268464 | 0.76 | TSHR (0.80) | KMT2AMEN1ALDH1A1MAPK1HPGD | |
| SCHEMBL24019591 | 0.75 | SMN1; SMN2 (0.69) | KMT2AMEN1ALDH1A1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3909577-A1 | UBIQUITIN-LIGASE INHIBITORS FOR THE TREATMENT OF CANCER | Fundación Profesor Novoa Santos (ES) | 2021-11-17 | — | — | EP | disclosed |