Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2402141 | 1.00 | TTR (0.55) | TTRALDH1A1GPR35TP53HPGD | |
| SCHEMBL427368 | 0.88 | ALDH1A1 (0.55) | TTRALDH1A1GPR35TP53HPGD | |
| SCHEMBL29821424 | 0.88 | ALDH1A1 (0.55) | TTRALDH1A1GPR35TP53HPGD | |
| SCHEMBL1220299 | 0.88 | ALDH1A1 (0.55) | TTRALDH1A1GPR35TP53HPGD | |
| SCHEMBL29379815 | 0.88 | ALDH1A1 (0.55) | TTRALDH1A1GPR35TP53HPGD | |
| SCHEMBL1322478 | 0.87 | TTR (0.52) | TTRALDH1A1GPR35TP53HPGD | |
| SCHEMBL1322476 | 0.87 | TTR (0.52) | TTRALDH1A1GPR35TP53HPGD | |
| SCHEMBL3639263 | 0.86 | HTT (0.47) | TTRALDH1A1GPR35TP53HPGD | |
| SCHEMBL823705 | 0.85 | RECQL (0.56) | TTRALDH1A1GPR35TP53HPGD | |
| SCHEMBL1268183 | 0.85 | ALDH1A1 (0.51) | TTRALDH1A1GPR35TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995008561-A1 | SYNTHESES OF AZAPEPTIDES BY THE FMOC/TERT-BUTYL/POLYAMIDE TECHNIQUE | MEDICAL RESEARCH COUNCIL (GB) | 1995-03-30 | — | — | WO | claimed |
| EP-1891142-B1 | OLIGO- AND POLY-CARBONATES TERMINATED WITH SILICON CONTAINING GROUPS AS SURFACE MODIFIERS | CIBA HOLDING INC (CH) | 2014-12-03 | — | — | EP | disclosed |
| US-20110224443-A1 | PREPARATION OF FOSAMPRENAVIR CALCIUM | DR. REDDY'S LABORATORIES LIMITED (IN) | 2011-09-15 | — | — | US | disclosed |
| US-8013047-B2 | Oligo- and poly-carbonates terminated with silicon containing groups as surface modifiers | BASF SE Ludwigshafen (DE) | 2011-09-06 | — | — | US | disclosed |
| EP-1984440-B1 | AROMATIC SULPHONATE FLAME RETARDANT COMPOSITIONS | BASF SE (DE) | 2010-11-03 | — | — | EP | disclosed |
| EP-1915427-B1 | POLYCARBONATE FLAME RETARDENT COMPOSITIONS | BASF SE (DE) | 2010-07-14 | — | — | EP | disclosed |
| US-20100168295-A1 | Polycarbonate Flame Retardant Compositions | CIBA CORPORATION | 2010-07-01 | — | — | US | disclosed |
| US-20100069537-A1 | Aromatic Sulphonate Flame Retardant Compositions | CIBA CORPORATION | 2010-03-18 | — | — | US | disclosed |
| US-20100010135-A1 | Oligo-and poly-carbonates terminated with silicon containing groups as surface modifiers | CIBA SPECIALTY CHEMICALS CORPORATION | 2010-01-14 | — | — | US | disclosed |
| US-20090062436-A1 | Aromatic Phosphate Acid Flame Retardant Compositions | CIBA CORP. | 2009-03-05 | — | — | US | disclosed |
| WO-2007093513-A1 | AROMATIC SULPHONATE FLAME RETARDANT COMPOSITIONS | CIBA HOLDING INC. (CH) | 2007-08-23 | — | — | WO | disclosed |
| US-7199215-B1 | comprising a novel carbaza unit significantly modifying the peptide backbone; for diagnosis of pathology conditions associated with the presence of endogenous or exogenous proteins; immunotherapy, vaccination | BIOMERIEUX (FR) | 2007-04-03 | — | — | US | disclosed |
| WO-2007020211-A1 | POLYCARBONATE FLAME RETARDENT COMPOSITIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-02-22 | — | — | WO | disclosed |
| WO-2006134045-A1 | OLIGO- AND POLY-CARBONATES TERMINATED WITH SILICON CONTAINING GROUPS AS SURFACE MODIFIERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-12-21 | — | — | WO | disclosed |
| WO-1995008561-A1 | SYNTHESES OF AZAPEPTIDES BY THE FMOC/TERT-BUTYL/POLYAMIDE TECHNIQUE | MEDICAL RESEARCH COUNCIL (GB) | 1995-03-30 | — | — | WO | disclosed |
| EP-0303842-A3 | CYCLIC POLYCARBONATE OLIGOMERS: INHIBITION OF POLYMERIZATION TO LINEAR POLYCARBONATES | GENERAL ELECTRIC COMPANY (US) | 1990-08-01 | — | — | EP | disclosed |
| US-4839462-A | SUBSTITUTED PHENOL AND PHENYL CARBONATE | GENERAL ELECTRIC COMPANY (US) | 1989-06-13 | — | — | US | disclosed |
| US-4839462-A | SUBSTITUTED PHENOL AND PHENYL CARBONATE | GENERAL ELECTRIC COMPANY (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0303842-A2 | Cyclic polycarbonate oligomers: inhibition of polymerization to linear polycarbonates | GENERAL ELECTRIC COMPANY (US) | 1989-02-22 | — | — | EP | disclosed |
| EP-0303842-A2 | Cyclic polycarbonate oligomers: inhibition of polymerization to linear polycarbonates | GENERAL ELECTRIC COMPANY (US) | 1989-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062436-A1 | Aromatic Phosphate Acid Flame Retardant Compositions | FGFR4, FFAR4, UPP1 | TTR 285/4885ALDH1A1 1199/4885GPR35 1173/4885 |
| US-20110224443-A1 | PREPARATION OF FOSAMPRENAVIR CALCIUM | ORAI1, CACNA1I, FOS | TTR 1724/4885ALDH1A1 3907/4885GPR35 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.