Sugi Predict

Sugi Predict / Compounds / SCHEMBL24022124

SCHEMBL24022124

SCHEMBL24022124

CCn1c2cc(Oc3ccccc3)ccc2c2ccc(N(c3ccccc3)c3ccc4c(c3)C3(c5ccccc5Oc5ccccc53)c3cc(N(c5ccccc5)c5ccc6c7ccc(Oc8ccccc8)cc7n(CC)c6c5)ccc3-4)cc21

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.36
▸ TDP1 Q9NUW8 2/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ METAP2 P50579 1/20 0.36
▸ ACSS2 Q9NR19 1/20 0.33
▸ TP53 P04637 2/20 0.32
▸ POLB P06746 1/20 0.32
▸ PDK2 Q15119 1/20 0.32
▸ LMNA P02545 1/20 0.31
▸ MAOA P21397 1/20 0.31
▸ MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24022119 0.95 MAPT (0.35) MAPTTDP1L3MBTL1METAP2ACSS2
SCHEMBL21940154 0.92 DYRK1A (0.36) MAPTMETAP2ACSS2POLBLMNA
SCHEMBL21939876 0.91 METAP2 (0.39) MAPTTDP1METAP2ACSS2PDK2
SCHEMBL21940164 0.91 MAPT (0.34) MAPTTDP1L3MBTL1ACSS2TP53
SCHEMBL21939877 0.87 METAP2 (0.37) MAPTMETAP2ACSS2PDK2MAOA
SCHEMBL21939953 0.87 NLRP3 (0.30) —
SCHEMBL24022118 0.86 GRIK2 (0.37) MAPTTDP1L3MBTL1POLBPDK2
SCHEMBL21940157 0.86 KDM4E (0.38) MAPTTDP1L3MBTL1POLBLMNA
SCHEMBL24022133 0.85 METAP2 (0.37) MAPTMETAP2PDK2
SCHEMBL21939619 0.84 METAP2 (0.35) METAP2ACSS2MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11177403-B2 Perovskite solar cell KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2021-11-16 — — US disclosed