Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2892603 | 0.85 | TSHR (0.44) | OPRM1SPHK1LMNADNM1FDPS | |
| SCHEMBL20054079 | 0.85 | TSHR (0.44) | OPRM1SPHK1LMNADNM1FDPS | |
| SCHEMBL24658493 | 0.85 | TSHR (0.44) | OPRM1SPHK1LMNADNM1FDPS | |
| SCHEMBL23230268 | 0.84 | LMNA (0.40) | OPRM1LMNA | |
| SCHEMBL11888376 | 0.83 | OPRM1 (0.40) | OPRM1CA1SPHK1LMNATP53 | |
| SCHEMBL11436878 | 0.82 | OPRM1 (0.41) | OPRM1SPHK1TP53DNM1TSHR | |
| SCHEMBL24071227 | 0.81 | LMNA (0.41) | OPRM1SPHK1LMNADNM1FDPS | |
| SCHEMBL18704696 | 0.81 | LMNA (0.41) | OPRM1SPHK1LMNADNM1FDPS | |
| SCHEMBL11398617 | 0.78 | OPRM1 (0.40) | OPRM1CA1SPHK1LMNATP53 | |
| Ammonia Solution, Strong SCHEMBL7194190 | 0.77 | OPRM1 (0.55) | OPRM1CA1SPHK1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3560503-B1 | RNA INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS | PHIO PHARM CORP (US) | 2021-11-17 | — | — | EP | disclosed |