Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18823623 | 1.00 | EPHX1 (0.55) | EPHX1SMN1; SMN2NPC1ALDH1A1CYP3A4 | |
| SCHEMBL23618281 | 0.85 | SIGMAR1 (0.46) | EPHX1SMN1; SMN2NPC1ALDH1A1CYP3A4 | |
| SCHEMBL25484597 | 0.85 | SIGMAR1 (0.46) | EPHX1SMN1; SMN2NPC1ALDH1A1CYP3A4 | |
| SCHEMBL19142695 | 0.81 | SIGMAR1 (0.43) | EPHX1SMN1; SMN2NPC1ALDH1A1CYP3A4 | |
| SCHEMBL18972635 | 0.79 | EPHX1 (0.46) | EPHX1SMN1; SMN2NPC1ALDH1A1CYP3A4 | |
| SCHEMBL10287540 | 0.78 | EPHX1 (0.50) | EPHX1SMN1; SMN2NPC1ALDH1A1CYP3A4 | |
| SCHEMBL18807454 | 0.78 | EPHX1 (0.50) | EPHX1SMN1; SMN2NPC1ALDH1A1CYP3A4 | |
| SCHEMBL8336708 | 0.78 | EPHX1 (0.50) | EPHX1SMN1; SMN2NPC1ALDH1A1CYP3A4 | |
| SCHEMBL23989085 | 0.78 | SIGMAR1 (0.41) | EPHX1SMN1; SMN2NPC1ALDH1A1CYP3A4 | |
| SCHEMBL16076630 | 0.78 | EPHX1 (0.43) | EPHX1SMN1; SMN2NPC1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572355-B2 | Methods for synthesizing vinylidenes and alkenes | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2023-02-07 | — | — | US | disclosed |
| US-20220017494-A1 | METHODS FOR SYNTHESIZING VINYLIDENES AND ALKENES | UNITED STATES DEPARTMENT OF ENERGY | 2022-01-20 | — | — | US | disclosed |
| US-11174350-B2 | Resin and photosensitive resin composition | TORAY INDUSTRIES, INC. (JP) | 2021-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572355-B2 | Methods for synthesizing vinylidenes and alkenes | ALKBH2, VAV1, ALKBH3 | EPHX1 2817/4885SMN1; SMN2 2289/4885NPC1 1472/4885 |
| US-20220017494-A1 | METHODS FOR SYNTHESIZING VINYLIDENES AND ALKENES | ALKBH2, VAV1, ALKBH3 | EPHX1 2817/4885SMN1; SMN2 2289/4885NPC1 1472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.