Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24039028 | 0.87 | MAP4K4 (0.37) | HDAC8HDAC6PLAUNEU3HDAC2 | |
| SCHEMBL24038700 | 0.86 | PARP1 (0.41) | MAPTALDH1A1NPC1RAB9ATPMT | |
| SCHEMBL24022832 | 0.84 | PRSS1 (0.43) | GAAALDH1A1NPC1RAB9ATPMT | |
| SCHEMBL24022759 | 0.78 | MEN1 (0.44) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL15492141 | 0.78 | HDAC8 (0.52) | HDAC8HDAC6PLAUMMP13GAA | |
| SCHEMBL24039027 | 0.77 | NEU3 (0.48) | HDAC8HDAC6PLAUNEU3MMP13 | |
| SCHEMBL22043790 | 0.76 | PRSS1 (0.33) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL1003295 | 0.74 | TPMT (0.54) | HDAC8HDAC6MMP13GAAHDAC2 | |
| SCHEMBL24038968 | 0.74 | NPC1 (0.41) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL24039057 | 0.73 | SLC7A5 (0.34) | HDAC8HDAC6GAAHDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021228992-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | RIGSHOSPITALET (DK) | 2021-11-18 | — | — | WO | disclosed |
| EP-3909944-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | Rigshospitalet (DK) | 2021-11-17 | — | — | EP | disclosed |