Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 3/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | C1S | P09871 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24022832 | 0.88 | PRSS1 (0.43) | PARP1TPMTNPC1RAB9APRSS1 | |
| SCHEMBL24022753 | 0.86 | HDAC8 (0.36) | PARP1TPMTNPC1RAB9APRSS1 | |
| SCHEMBL24038958 | 0.83 | PARP1 (0.41) | PARP1DHODHPKMKDM4EMEN1 | |
| SCHEMBL22043790 | 0.80 | PRSS1 (0.33) | NPC1RAB9APRSS1PRSS2C1S | |
| SCHEMBL24022759 | 0.79 | MEN1 (0.44) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL12865158 | 0.78 | PARP1 (0.60) | PARP1DHODHTPMTPRSS1PRSS2 | |
| SCHEMBL24038968 | 0.78 | NPC1 (0.41) | PARP1NPC1RAB9APRSS1PRSS2 | |
| SCHEMBL24039068 | 0.75 | PTGS2 (0.32) | L3MBTL1 | |
| SCHEMBL22043792 | 0.75 | PARP1 (0.50) | PARP1NPC1RAB9APKMMEN1 | |
| SCHEMBL24022830 | 0.74 | MKNK1 (0.38) | NPC1RAB9APRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021228992-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | RIGSHOSPITALET (DK) | 2021-11-18 | — | — | WO | disclosed |