Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FURIN | P09958 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24022832 | 0.80 | PRSS1 (0.43) | ALDH1A1 | |
| SCHEMBL24038700 | 0.79 | PARP1 (0.41) | MEN1KMT2ACYP3A4THRBLMNA | |
| SCHEMBL24022753 | 0.78 | HDAC8 (0.36) | MEN1KMT2ATHRBTDP1ALDH1A1 | |
| SCHEMBL24022841 | 0.74 | NEU3 (0.46) | MEN1KMT2ACYP1A2LMNAALDH1A1 | |
| SCHEMBL22043790 | 0.73 | PRSS1 (0.33) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10148977 | 0.72 | TPMT (0.59) | MEN1KMT2AHSD17B10THRBLMNA | |
| SCHEMBL12781878 | 0.71 | MEN1 (0.70) | MEN1KMT2AHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL849875 | 0.71 | MEN1 (0.77) | MEN1KMT2AHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL24038968 | 0.71 | NPC1 (0.41) | MEN1KMT2ACYP3A4MAPTATM | |
| SCHEMBL24022836 | 0.70 | HDAC1 (0.62) | CYP1A2CYP3A4ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3909944-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | Rigshospitalet (DK) | 2021-11-17 | — | — | EP | disclosed |