Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 4/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24022801 | 0.84 | PLK1 (0.39) | METHDAC6 | |
| SCHEMBL22147523 | 0.83 | FAAH (0.40) | HDAC4HDAC6ALOX5APFEN1 | |
| SCHEMBL24022799 | 0.82 | TP53 (0.36) | GAAMETPIK3CAMTORHDAC6 | |
| SCHEMBL22043784 | 0.82 | NPC1 (0.43) | GAA | |
| SCHEMBL15662716 | 0.81 | RARB (0.44) | — | |
| SCHEMBL22043758 | 0.80 | DGAT1 (0.49) | MAPK1ALOX5APFEN1PDE2APDE10A | |
| SCHEMBL24333878 | 0.77 | ALOX5AP (0.40) | GAAMTORALOX5APFEN1PDE10A | |
| SCHEMBL22044463 | 0.76 | MIF (0.37) | HDAC4HDAC6 | |
| SCHEMBL24334466 | 0.76 | PLK1 (0.53) | HDAC4HDAC6 | |
| SCHEMBL15074690 | 0.75 | GAA (0.61) | GAAMETMAPK1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021228992-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | RIGSHOSPITALET (DK) | 2021-11-18 | — | — | WO | disclosed |
| EP-3909944-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | Rigshospitalet (DK) | 2021-11-17 | — | — | EP | disclosed |