Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17160038 | 0.74 | ALDH1A1 (0.42) | CYP2C9ALDH1A1GAAUSP2PKM | |
| SCHEMBL16240943 | 0.74 | ALDH1A1 (0.42) | CYP2C9ALDH1A1GAAUSP2PKM | |
| SCHEMBL24023635 | 0.72 | TYR (0.34) | CYP2C9ALDH1A1GAALMNA | |
| SCHEMBL25599236 | 0.69 | TYR (0.38) | CYP2C9ALDH1A1GAASCN10ALMNA | |
| SCHEMBL25695775 | 0.67 | LMNA (0.44) | CYP2C9ALDH1A1GAAPKMALOX15 | |
| SCHEMBL22023861 | 0.66 | USP2 (0.37) | CYP2C9ALDH1A1GAAUSP2PKM | |
| SCHEMBL28204581 | 0.65 | TYR (0.43) | ALDH1A1GAAHPGDALOX15SCN10A | |
| SCHEMBL19187436 | 0.65 | ALDH1A1 (0.42) | CYP2C9ALDH1A1GAAUSP2PKM | |
| SCHEMBL19102522 | 0.64 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL11517329 | 0.64 | ALDH1A1 (0.48) | CYP2C9ALDH1A1GAAUSP2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210355103-A1 | PARG INHIBITORS AND METHOD OF USE THEREOF | CITY OF HOPE | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210355103-A1 | PARG INHIBITORS AND METHOD OF USE THEREOF | PARG, PARP12, PARN | CYP2C9 792/4885ALDH1A1 2378/4885GAA 1006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.