Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | EIF4E | P06730 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | TOP1 | P11387 | 1/20 | 0.70 |
| ▸ | THPO | P40225 | 1/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | PNP | P00491 | 3/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.50 |
| ▸ | ATIC | P31939 | 2/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24024426 | 1.00 | LMNA (0.70) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL13606969 | 0.90 | PNP (0.69) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL6555263 | 0.88 | LMNA (0.73) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL24024530 | 0.86 | LMNA (0.61) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| Ribavirin SCHEMBL1200226 | 0.86 | LMNA (0.90) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| Ribavirin SCHEMBL572829 | 0.86 | LMNA (0.90) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL24024753 | 0.85 | LMNA (0.62) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL24024521 | 0.85 | LMNA (0.62) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL24024516 | 0.85 | LMNA (0.62) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| Ribavirin SCHEMBL5473652 | 0.85 | LMNA (0.88) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210353660-A1 | Pre-Activated Nucleoside IMPDH Inhibitors As Anti-Infective Drugs | OCTAGON THERAPEUTICS INC. (US) | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210353660-A1 | Pre-Activated Nucleoside IMPDH Inhibitors As Anti-Infective Drugs | IMPDH1, IMPDH2, PNP | LMNA 1199/4885SMN1; SMN2 4411/4885ADORA1 420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.