Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 2/20 | 0.71 |
| ▸ | FBP1 | P09467 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | ATG7 | O95352 | 9/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | TYMP | P19971 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12918453 | 0.86 | ATIC (0.74) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL13153880 | 0.86 | ATIC (0.74) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL14469426 | 0.85 | ATIC (0.72) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL1230585 | 0.83 | ATIC (1.00) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL4359472 | 0.83 | ATIC (1.00) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL1230589 | 0.83 | ATIC (1.00) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL849848 | 0.83 | ATIC (1.00) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL20276955 | 0.83 | ATIC (1.00) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL20134003 | 0.83 | ATIC (1.00) | ATICFBP1KDM4ETDP1TP53 | |
| SCHEMBL15520399 | 0.83 | ATIC (1.00) | ATICFBP1KDM4ETDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210353660-A1 | Pre-Activated Nucleoside IMPDH Inhibitors As Anti-Infective Drugs | OCTAGON THERAPEUTICS INC. (US) | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210353660-A1 | Pre-Activated Nucleoside IMPDH Inhibitors As Anti-Infective Drugs | IMPDH1, IMPDH2, PNP | ATIC 86/4885FBP1 527/4885KDM4E 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.