Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.55 |
| ▸ | TACR3 | P29371 | 5/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30647460 | 0.85 | NCOA1 (0.57) | NCOA1NCOA3TACR3DHODHGRM2 | |
| SCHEMBL30647462 | 0.85 | NCOA1 (0.46) | NCOA1NCOA3TACR3DHODHGRM2 | |
| SCHEMBL4563284 | 0.83 | NCOA1 (0.52) | NCOA1NCOA3TACR3DHODHGRM2 | |
| SCHEMBL2511408 | 0.83 | PARP1 (0.43) | NCOA1NCOA3SMN1; SMN2IKBKBAURKA | |
| SCHEMBL30647505 | 0.82 | NCOA1 (0.53) | NCOA1NCOA3TACR3DHODHGRM2 | |
| SCHEMBL30647468 | 0.81 | NCOA1 (0.43) | NCOA1NCOA3TACR3DHODHGRM2 | |
| SCHEMBL30647497 | 0.81 | NCOA1 (0.47) | NCOA1NCOA3GRM2TSHRSMN1; SMN2 | |
| SCHEMBL30647456 | 0.81 | NCOA1 (0.47) | NCOA1NCOA3DHODHGRM2TSHR | |
| SCHEMBL2462376 | 0.80 | NCOA1 (0.54) | NCOA1NCOA3TACR3GRM2SMN1; SMN2 | |
| SCHEMBL2402873 | 0.80 | NCOA1 (0.54) | NCOA1NCOA3TACR3GRM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119693-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |