Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | FAP | Q12884 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | KDM5A | P29375 | 1/20 | 0.52 |
| ▸ | KDM5C | P41229 | 1/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30135587 | 0.81 | NSD2 (0.62) | NSD2FAPKDM5B | |
| SCHEMBL15129718 | 0.81 | NSD2 (0.62) | NSD2FAPKDM5B | |
| SCHEMBL10243020 | 0.81 | HTT (0.60) | NSD2FAPTP53GAAKDM4E | |
| SCHEMBL15661203 | 0.80 | PSMD14 (0.60) | NSD2MAPTRAB9ANPC1EGLN1 | |
| SCHEMBL12903049 | 0.80 | NSD2 (0.59) | NSD2FAP | |
| SCHEMBL5016070 | 0.80 | NSD2 (0.53) | NSD2FAPKMT2A | |
| SCHEMBL13406169 | 0.79 | HTT (0.60) | MAPTGAAKDM4EPOLB | |
| SCHEMBL14075095 | 0.77 | NSD2 (0.51) | NSD2FAPKMT2A | |
| SCHEMBL9001093 | 0.77 | KDM4E (0.61) | NSD2MAPTRAB9ATP53NPC1 | |
| SCHEMBL5603305 | 0.77 | NSD2 (0.56) | NSD2FAPGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119693-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |