Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.62 |
| ▸ | PREP | P48147 | 5/20 | 0.55 |
| ▸ | FAP | Q12884 | 11/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.54 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15129718 | 1.00 | NSD2 (0.62) | NSD2PREPFAPDPP7PITRM1 | |
| SCHEMBL24928102 | 0.84 | FAP (0.63) | NSD2PREPFAPDPP7PITRM1 | |
| SCHEMBL12903049 | 0.83 | NSD2 (0.59) | NSD2PREPFAPDPP7PITRM1 | |
| SCHEMBL13101452 | 0.83 | FAP (0.53) | NSD2PREPFAPDPP7PITRM1 | |
| SCHEMBL22367618 | 0.81 | EGLN1 (0.45) | NSD2PREPDPP9FTOKDM5B | |
| SCHEMBL2402489 | 0.81 | NSD2 (0.65) | NSD2FAPKDM5B | |
| SCHEMBL5603305 | 0.81 | NSD2 (0.56) | NSD2PREPFAPDPP7HDAC3 | |
| SCHEMBL21101481 | 0.81 | NSD2 (0.57) | NSD2PREPFAPDPP7PITRM1 | |
| SCHEMBL26965980 | 0.80 | PREP (0.57) | NSD2PREPDPP9FTO | |
| SCHEMBL31461294 | 0.80 | EGLN1 (0.51) | PREPFTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240335569-A1 | FIBROBLAST ACTIVATION PROTEIN INHIBITORS AND USE THEREOF | 3 B Pharmaceuticals GmbH (DE) | 2024-10-10 | — | — | US | disclosed |
| EP-4373529-A1 | FIBROBLAST ACTIVATION PROTEIN INHIBITORS AND USE THEREOF | 3B Pharmaceuticals GmbH (DE) | 2024-05-29 | — | — | EP | disclosed |
| CN-117769443-A | Fibroblast activation protein inhibitor and use thereof | 3B制药有限公司 | 2024-03-26 | — | — | CN | disclosed |
| WO-2023002045-A1 | FIBROBLAST ACTIVATION PROTEIN INHIBITORS AND USE THEREOF | 3B PHARMACEUTICALS GMBH (DE) | 2023-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240335569-A1 | FIBROBLAST ACTIVATION PROTEIN INHIBITORS AND USE THEREOF | FIBP, FGF2, FGFR2 | NSD2 3751/4885PREP 716/4885FAP 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.