Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29232480 | 0.98 | MAPT (0.49) | MAPTALDH1A1GAAADRA1DCYP3A4 | |
| SCHEMBL8339184 | 0.82 | ADRA1D (0.43) | MAPTADRA1DCYP3A4MEN1CYP1A2 | |
| SCHEMBL9769575 | 0.81 | MAPT (0.42) | MAPTALDH1A1GAACYP3A4IDO1 | |
| SCHEMBL13232801 | 0.79 | KDM4E (0.46) | ALDH1A1GAAADRA1DCYP3A4MEN1 | |
| SCHEMBL9516851 | 0.79 | MAPT (0.41) | MAPTALDH1A1GAACYP3A4IDO1 | |
| SCHEMBL18233608 | 0.78 | BCHE (0.43) | ALDH1A1ADRA1DCYP3A4MEN1CYP1A2 | |
| SCHEMBL29792680 | 0.78 | LOX (0.49) | GAAADRA1DCYP3A4MEN1CYP1A2 | |
| SCHEMBL1146006 | 0.78 | LOX (0.49) | GAAADRA1DCYP3A4MEN1CYP1A2 | |
| SCHEMBL2024322 | 0.77 | CTSB (0.53) | ALDH1A1ADRA1DCYP3A4MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL567914 | 0.76 | LOX (0.47) | GAAADRA1DCYP3A4MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11220508-B2 | TYK2 inhibitors and uses thereof | NIMBUS LAKSHMI, INC. (US) | 2022-01-11 | — | — | US | disclosed |
| US-11174265-B2 | — | — | 2021-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11220508-B2 | TYK2 inhibitors and uses thereof | TYK2, JAK2, JAK1 | MAPT 1236/4885ALDH1A1 4827/4885GAA 1899/4885 |
| US-11174265-B2 | — | TYK2, JAK2, JAK1 | MAPT 826/4885ALDH1A1 4709/4885GAA 2099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.