SCHEMBL24026871

SCHEMBL24026871

c1ccc2c(c1)cc1c3cc4c5c6ccccc6cc6c7ccccc7n(c4cc3n3c4ccccc4c2c13)c65

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.34
ALDH1A1 P00352 2/20 0.34
HIF1A Q16665 1/20 0.34
CYP1B1 Q16678 1/20 0.34
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
CASP1 P29466 1/20 0.33
GALK1 P51570 1/20 0.33
BLM P54132 1/20 0.33
CASP7 P55210 1/20 0.33
KMT2A Q03164 1/20 0.33
SAE1 Q9UBE0 1/20 0.33
UBA2 Q9UBT2 1/20 0.33
CDC25B P30305 1/20 0.32
KDM4E B2RXH2 3/20 0.31
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
RCE1 Q9Y256 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24026869 0.97 HSD17B10 (0.36) HSD17B10ALDH1A1HIF1ACYP1B1GAA
SCHEMBL24026873 0.97 HSD17B10 (0.36) HSD17B10ALDH1A1HIF1ACYP1B1GAA
SCHEMBL20857845 0.92 HSD17B10 (0.38) HSD17B10ALDH1A1HIF1ACYP1B1GAA
SCHEMBL20857867 0.92 HSD17B10 (0.38) HSD17B10ALDH1A1HIF1ACYP1B1GAA
SCHEMBL21710490 0.92 HSD17B10 (0.40) HSD17B10ALDH1A1HIF1ACYP1B1GAA
SCHEMBL24026865 0.91 ALDH1A1 (0.35) HSD17B10ALDH1A1HIF1ACYP1B1GAA
SCHEMBL24026868 0.91 ALDH1A1 (0.35) HSD17B10ALDH1A1HIF1ACYP1B1GAA
SCHEMBL24026879 0.91 ALDH1A1 (0.35) HSD17B10ALDH1A1HIF1ACYP1B1GAA
SCHEMBL22868315 0.90 HSD17B10 (0.34) HSD17B10ALDH1A1HIF1ACYP1B1GAA
SCHEMBL24026880 0.89 ALDH1A1 (0.33) HSD17B10ALDH1A1HIF1ACYP1B1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210359221-A1 COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2021-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210359221-A1 COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS USING THE SAME HAX1, AFF4, XPO4 HSD17B10 2905/4885ALDH1A1 1065/4885HIF1A 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.