Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24027047 | 0.89 | ESR1 (0.59) | ESR1 | |
| SCHEMBL23794112 | 0.88 | ESR1 (0.74) | ESR1 | |
| SCHEMBL22881884 | 0.87 | ESR1 (0.62) | ESR1 | |
| SCHEMBL19760652 | 0.86 | ESR1 (0.78) | ESR1 | |
| SCHEMBL22002256 | 0.86 | ESR1 (0.78) | ESR1 | |
| SCHEMBL19760665 | 0.86 | ESR1 (0.78) | ESR1 | |
| SCHEMBL22213732 | 0.84 | ESR1 (0.60) | ESR1 | |
| SCHEMBL17858935 | 0.81 | ESR1 (0.67) | ESR1 | |
| SCHEMBL17858907 | 0.81 | ESR1 (0.66) | ESR1 | |
| SCHEMBL23793738 | 0.80 | ESR1 (0.73) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3472162-B1 | HETEROARYL ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2021-11-17 | — | — | EP | disclosed |