Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 4/20 | 0.32 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.32 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | GNRHR | P30968 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24027765 | 0.90 | MAPT (0.37) | MAPTALDH1A1SMN1; SMN2PARP1BRD4 | |
| SCHEMBL20543577 | 0.89 | THRB (0.38) | PDE3BPDE3AMAPTALDH1A1NPC1 | |
| SCHEMBL20543509 | 0.89 | GAA (0.37) | PDE3BPDE3AMAPTALDH1A1NPC1 | |
| SCHEMBL20543625 | 0.87 | GNRHR (0.40) | ALDH1A1NPC1RAB9AGNRHRMEN1 | |
| SCHEMBL20543506 | 0.85 | GAA (0.37) | PDE3BPDE3AMAPTALDH1A1NPC1 | |
| SCHEMBL20548364 | 0.84 | GAA (0.35) | PDE3BPDE3AMAPTALDH1A1NPC1 | |
| SCHEMBL21879026 | 0.81 | NPC1 (0.38) | PDE3BPDE3AMAPTALDH1A1NPC1 | |
| SCHEMBL20543416 | 0.80 | NPC1 (0.33) | PDE3BPDE3AMAPTALDH1A1NPC1 | |
| SCHEMBL20543580 | 0.80 | MAPT (0.35) | PDE3BPDE3AMAPTALDH1A1NPC1 | |
| SCHEMBL19206704 | 0.80 | PARP1 (0.43) | ALDH1A1POLBTP53PARP1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615516-B1 | IMIDAZOPYRAZINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND THEIR USES AS LUCIFERINS | PASTEUR INSTITUT (FR) | 2021-11-17 | — | — | EP | disclosed |