Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 6/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24027401 | 0.90 | PDE3B (0.35) | MAPTBRD4PARP1ALDH1A1MEN1 | |
| SCHEMBL19206704 | 0.90 | PARP1 (0.43) | BRD4PARP1ALDH1A1MEN1CYP1A2 | |
| SCHEMBL19206673 | 0.89 | MAPT (0.41) | MAPTPARP1CDC7ALDH1A1KDM4E | |
| SCHEMBL492636 | 0.88 | LTB4R (0.41) | MAPTPARP1CDC7LTB4RALDH1A1 | |
| SCHEMBL20543611 | 0.88 | THRB (0.42) | MAPTCDC7ALDH1A1MEN1KMT2A | |
| SCHEMBL19206676 | 0.87 | LTB4R (0.38) | MAPTCDC7LTB4RALDH1A1HSD17B10 | |
| SCHEMBL19206672 | 0.87 | CDC7 (0.38) | MAPTCDC7LTB4RALDH1A1HSD17B10 | |
| SCHEMBL19206693 | 0.86 | POLB (0.38) | CDC7LTB4RALDH1A1KMT2AHSD17B10 | |
| SCHEMBL19206663 | 0.86 | NMT1 (0.38) | PARP1CDC7LTB4RALKBH3PSD | |
| SCHEMBL20543423 | 0.86 | PDE3B (0.38) | MAPTCDC7LTB4RALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615516-B1 | IMIDAZOPYRAZINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND THEIR USES AS LUCIFERINS | PASTEUR INSTITUT (FR) | 2021-11-17 | — | — | EP | disclosed |