Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25214857 | 0.80 | LMNA (0.51) | LMNAMEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL1420853 | 0.76 | IDH2 (0.66) | IDH2RAPGEF4L3MBTL1MEN1KMT2A | |
| SCHEMBL31395652 | 0.76 | IDH2 (0.66) | IDH2RAPGEF4L3MBTL1MEN1KMT2A | |
| SCHEMBL30212852 | 0.76 | LMNA (0.50) | LMNAL3MBTL1MEN1KMT2ATP53 | |
| SCHEMBL24027843 | 0.76 | LMNA (0.50) | LMNAL3MBTL1MEN1KMT2ATP53 | |
| SCHEMBL24027852 | 0.76 | TSHR (0.55) | SLC6A4ALDH1A1TDP1 | |
| SCHEMBL30213082 | 0.76 | TSHR (0.55) | SLC6A4ALDH1A1TDP1 | |
| SCHEMBL24027853 | 0.76 | CA1 (0.45) | LMNASLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL30255954 | 0.75 | RXFP1 (0.54) | LMNAL3MBTL1MEN1KMT2ATP53 | |
| SCHEMBL24027840 | 0.75 | RXFP1 (0.54) | LMNAL3MBTL1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021229571-A1 | IMIDAZOLE 3-OXIDE DERIVATIVE BASED ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD (IL) | 2021-11-18 | — | — | WO | disclosed |