Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24209699 | 0.90 | HPGD (0.79) | HPGDMEN1KMT2AMAPK1ATM | |
| SCHEMBL24019599 | 0.79 | HPGD (1.00) | HPGDMEN1KMT2AMAPK1ATM | |
| SCHEMBL24019591 | 0.78 | SMN1; SMN2 (0.69) | HPGDMEN1KMT2AMAPK1ATM | |
| SCHEMBL24019594 | 0.77 | TP53 (0.72) | HPGDMEN1KMT2AMAPK1ATM | |
| SCHEMBL24019601 | 0.77 | HPGD (0.62) | HPGDMEN1KMT2AMAPK1ATM | |
| SCHEMBL21951986 | 0.76 | MAPT (0.71) | HPGDMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL24019574 | 0.76 | HPGD (0.80) | HPGDMEN1KMT2AMAPK1ATM | |
| SCHEMBL16268464 | 0.76 | TSHR (0.80) | HPGDMEN1KMT2AMAPK1ATM | |
| SCHEMBL24029199 | 0.76 | ALDH1A1 (0.70) | HPGDMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL22010011 | 0.75 | HPGD (0.67) | HPGDMEN1KMT2AMAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021229035-A1 | UBIQUITIN-LIGASE INHIBITORS FOR THE TREATMENT OF CANCER | FUNDACIÓN PROFESOR NOVOA SANTOS (ES) | 2021-11-18 | — | — | WO | disclosed |