Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 14/20 | 0.41 |
| ▸ | CTSK | P43235 | 12/20 | 0.41 |
| ▸ | CTSL | P07711 | 12/20 | 0.41 |
| ▸ | CTSS | P25774 | 11/20 | 0.41 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24029296 | 0.72 | — | — | |
| SCHEMBL11687449 | 0.72 | DPP4 (0.33) | DPP4 | |
| SCHEMBL14223436 | 0.71 | PHF8 (0.35) | DPP4 | |
| SCHEMBL10158912 | 0.67 | — | — | |
| SCHEMBL28335145 | 0.65 | — | — | |
| SCHEMBL4546667 | 0.65 | DPP4 (0.66) | DPP4 | |
| SCHEMBL23901083 | 0.65 | — | — | |
| SCHEMBL282872 | 0.64 | — | — | |
| SCHEMBL26767654 | 0.64 | MLYCD (0.32) | — | |
| SCHEMBL4546670 | 0.62 | CASP1 (0.45) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231778-A1 | CORONAVIRUS PROTEASE DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-11-18 | — | — | WO | disclosed |