Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.44 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24030004 | 0.81 | SLC5A1 (0.47) | LMNATSHRALDH1A1SLC5A1SLC5A2 | |
| SCHEMBL24897568 | 0.79 | MEN1 (0.38) | NPC1RAB9AMAPTTDP1TSHR | |
| SCHEMBL24030017 | 0.76 | LTA4H (0.41) | NPC1RAB9ALTA4HSLC5A1SLC5A2 | |
| SCHEMBL21028847 | 0.76 | SLC5A1 (0.66) | NPC1RAB9ALMNAMAPTTSHR | |
| SCHEMBL21028740 | 0.76 | L3MBTL1 (0.48) | NPC1LMNAMAPTCASP3SENP8 | |
| SCHEMBL19034488 | 0.73 | SLC5A1 (0.49) | LMNALTA4HSLC5A1SLC5A2KMT2A | |
| SCHEMBL24038308 | 0.73 | LTA4H (0.47) | NPC1RAB9ATSHRLTA4HSLC5A1 | |
| SCHEMBL22995059 | 0.72 | SLC5A1 (0.59) | LTA4HALDH1A1SLC5A1SLC5A2KMT2A | |
| SCHEMBL20803452 | 0.72 | SLC5A1 (0.61) | NPC1RAB9ALMNAMAPTLTA4H | |
| SCHEMBL25493958 | 0.71 | NPC1 (0.48) | NPC1RAB9ALMNAMAPTCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021227440-A1 | A CLASS OF ARYL GLUCOSIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海喆邺生物科技有限公司 | 2021-11-18 | — | — | WO | disclosed |