Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LY6K | Q17RY6 | 1/20 | 0.67 |
| ▸ | KDM1A | O60341 | 7/20 | 0.64 |
| ▸ | GLA | P06280 | 2/20 | 0.64 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.64 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.64 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | TOP1 | P11387 | 1/20 | 0.64 |
| ▸ | TOP2A | P11388 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.64 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13524796 | 0.83 | KDM1A (0.72) | LY6KKDM1AGLATOP2BOPRD1 | |
| SCHEMBL13530937 | 0.82 | KDM1A (0.70) | LY6KKDM1AGLATOP2BOPRD1 | |
| SCHEMBL24030236 | 0.81 | LY6K (1.00) | LY6KKDM1AGLATOP2BOPRD1 | |
| SCHEMBL22401407 | 0.78 | LY6K (0.94) | LY6KKDM1AGLATOP2BOPRD1 | |
| Amsacrine SCHEMBL29360354 | 0.78 | TOP2B (1.00) | LY6KKDM1AGLATOP2BOPRD1 | |
| Amsacrine SCHEMBL29350869 | 0.78 | TOP2B (1.00) | LY6KKDM1AGLATOP2BOPRD1 | |
| Amsacrine SCHEMBL28336991 | 0.78 | TOP2B (1.00) | LY6KKDM1AGLATOP2BOPRD1 | |
| Amsacrine SCHEMBL6256280 | 0.78 | TOP2B (1.00) | LY6KKDM1AGLATOP2BOPRD1 | |
| Amsacrine SCHEMBL4047 | 0.78 | TOP2B (1.00) | LY6KKDM1AGLATOP2BOPRD1 | |
| SCHEMBL13529538 | 0.77 | KDM1A (0.67) | LY6KKDM1AGLATOP2BOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231893-A1 | COMPOUNDS FOR INHIBITING LY6K AND METHODS OF USING SAME | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2021-11-18 | — | — | WO | disclosed |