Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18366378 | 0.85 | KDM4E (0.42) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL24030244 | 0.83 | MAPK1 (0.35) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL17320978 | 0.76 | KDM4E (0.55) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL24030295 | 0.72 | AOC3 (0.34) | KMT2AKDM4ERAB9A | |
| SCHEMBL18357673 | 0.70 | KDM4E (0.32) | KDM4EGPR139 | |
| SCHEMBL26690104 | 0.69 | SMN1; SMN2 (0.37) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL15898831 | 0.69 | RBP4 (0.47) | KDM4ESMN1; SMN2ALDH1A1RAB9AMAPK1 | |
| SCHEMBL16946874 | 0.67 | PIM1 (0.41) | TGFBR1 | |
| SCHEMBL20400230 | 0.67 | KDM4E (0.40) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL26690301 | 0.66 | ALDH1A1 (0.36) | KMT2AKDM4ESMN1; SMN2ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021228248-A1 | FUSED AZA-HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | 石药集团中奇制药技术（石家庄）有限公司 | 2021-11-18 | — | — | WO | disclosed |