Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PARG | Q86W56 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1776113 | 0.75 | DDB1 (0.44) | ALDH1A1KDM4EKCNA5CRBNLMNA | |
| SCHEMBL4743569 | 0.75 | GBA1 (0.59) | GBA1ALDH1A1PKMKDM4EGAA | |
| SCHEMBL2041963 | 0.75 | KCNA5 (0.48) | ALDH1A1GAAKCNA5CRBN | |
| SCHEMBL2470122 | 0.74 | GBA1 (1.00) | GBA1ALDH1A1PKMCTSLCTSK | |
| SCHEMBL9834675 | 0.74 | GBA1 (0.78) | GBA1ALDH1A1PKMCTSLCTSK | |
| SCHEMBL14282764 | 0.73 | KMT2A (0.58) | GBA1ALDH1A1PKMKDM4EGAA | |
| SCHEMBL9834420 | 0.72 | GBA1 (0.69) | GBA1ALDH1A1PKMKDM4EGAA | |
| SCHEMBL8394068 | 0.71 | GBA1 (0.86) | GBA1ALDH1A1PKMCTSLCTSK | |
| SCHEMBL3811045 | 0.71 | GBA1 (0.86) | GBA1ALDH1A1PKMCTSLCTSK | |
| SCHEMBL13543087 | 0.71 | GBA1 (0.78) | GBA1ALDH1A1PKMKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212920-A1 | N-Substituted Benzene Sulfonamides | NEITZEL MARTIN | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212920-A1 | N-Substituted Benzene Sulfonamides | PSEN1, PSEN2, BACE1 | GBA1 367/4885ALDH1A1 897/4885PKM 3629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.