Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | CTSL | P07711 | 3/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.55 |
| ▸ | CTSB | P07858 | 2/20 | 0.55 |
| ▸ | PARG | Q86W56 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834420 | 0.91 | GBA1 (0.69) | GBA1ALDH1A1PKMCTSLCTSK | |
| SCHEMBL2470122 | 0.88 | GBA1 (1.00) | GBA1ALDH1A1PKMCTSLCTSK | |
| SCHEMBL3811045 | 0.85 | GBA1 (0.86) | GBA1ALDH1A1PKMCTSLCTSK | |
| SCHEMBL8394068 | 0.85 | GBA1 (0.86) | GBA1ALDH1A1PKMCTSLCTSK | |
| SCHEMBL9832352 | 0.84 | CNR1 (0.55) | GBA1ALDH1A1PKMPARGKMT2A | |
| SCHEMBL9833885 | 0.84 | GBA1 (0.55) | GBA1ALDH1A1PKMPARGKMT2A | |
| SCHEMBL8396377 | 0.83 | GBA1 (0.83) | GBA1ALDH1A1PKMCTSLCTSK | |
| SCHEMBL7886816 | 0.83 | GBA1 (0.83) | GBA1ALDH1A1PKMCTSLCTSK | |
| SCHEMBL9834810 | 0.82 | GBA1 (0.65) | GBA1ALDH1A1PKMCTSLCTSK | |
| SCHEMBL14606609 | 0.81 | GBA1 (0.84) | GBA1ALDH1A1PKMCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242518-B1 | Cycloalkano[1,2-b]indole-sulfonamides | BAYER AG (DE) | 1991-04-10 | — | — | EP | disclosed |
| US-4988820-A | Inhibiting platelet aggregation, anticoagulants, thromboxane a2 antagonist | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4965258-A | Anticoagulant; thromboxane a2 antagonist | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |
| US-4904797-A | REACTING A (BENZENESULFONAMIDOALKYL)CYCLOALKANO(1,2-B)INDOLE WITH ACRYLONITRILE; HYDROLYSIS, HYDROGENATION, REDUCTION | BAYER AKTIENGESELLSCHAFT (DE) | 1990-02-27 | — | — | US | disclosed |
| US-4827032-A | INTERMEDIATES FOR ANTICOAGULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-02 | — | — | US | disclosed |
| EP-0242518-A1 | Cycloalkano[1,2-b]indole-sulfonamides | BAYER AG (DE) | 1987-10-28 | — | — | EP | disclosed |