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Sugi Predict / Compounds / Nicotifloroside

Nicotifloroside

Nicotifloroside

SCHEMBL240355

C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(-c4ccc(O)cc4)oc4cc(O)cc(O)c4c3=O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ P4HB P07237 6/20 1.00
▸ XDH P47989 2/20 1.00
▸ POLB P06746 2/20 1.00
▸ GAA P10253 2/20 1.00
▸ APEX1 P27695 1/20 1.00
▸ RECQL P46063 1/20 1.00
▸ L3MBTL1 Q9Y468 1/20 1.00
▸ KDM4E B2RXH2 4/20 0.88
▸ MAPT P10636 3/20 0.88
▸ HES1 Q14469 2/20 0.88
▸ FANCF Q9NPI8 2/20 0.88
▸ ACHE P22303 2/20 0.88
▸ KDM1A O60341 1/20 0.88
▸ PRSS1 P07477 1/20 0.88
▸ PRSS2 P07478 1/20 0.88
▸ ADRA2A P08913 1/20 0.88
▸ HMGB1 P09429 1/20 0.88
▸ CFTR P13569 1/20 0.88
▸ ADRA2C P18825 1/20 0.88
▸ MAOA P21397 1/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Kaempferol-3-O-Rutinoside SCHEMBL14916541 1.00 P4HB (1.00) P4HBXDHPOLBGAAAPEX1
Nicotifloroside SCHEMBL29403154 1.00 P4HB (1.00) P4HBXDHPOLBGAAAPEX1
Kaempferol-3-O-Rutinoside SCHEMBL21013016 1.00 P4HB (1.00) P4HBXDHPOLBGAAAPEX1
Kaempferol-3-O-Rutinoside SCHEMBL15591885 1.00 P4HB (1.00) P4HBXDHPOLBGAAAPEX1
Kaempferol-3-O-Rutinoside SCHEMBL10000318 1.00 P4HB (1.00) P4HBXDHPOLBGAAAPEX1
Kaempferol-3-O-Rutinoside SCHEMBL29522866 1.00 P4HB (1.00) P4HBXDHPOLBGAAAPEX1
Kaempferol-3-O-Rutinoside SCHEMBL31720528 1.00 P4HB (1.00) P4HBXDHPOLBGAAAPEX1
SCHEMBL22678450 0.94 P4HB (0.89) P4HBXDHPOLBGAAAPEX1
SCHEMBL7591453 0.94 P4HB (0.89) P4HBXDHPOLBGAAAPEX1
SCHEMBL7591460 0.94 P4HB (0.89) P4HBXDHPOLBGAAAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4378448-B1 EXTRACT OF FLOWERS, LEAVES AND/OR SEED PODS OF IMPATIENS AND LEAVES OF PANDANUS, IN DRIED AND LIQUID FORM, A METHOD OF ITS OBTAINING AND USE THEREOF PBCLABS SP Z O O (PL) 2026-05-20 — — EP claimed
CN-115144485-B Characteristic fingerprint spectrum and content determination and quality control method of traditional Chinese medicine composition for treating chronic recurrent eczema 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） 2024-10-15 — — CN claimed
CN-118348138-A Detection method for chemical components in ginkgo biloba 北京振东光明药物研究院有限公司 2024-07-16 — — CN claimed
EP-4378448-A1 EXTRACT OF FLOWERS, LEAVES AND/OR SEED PODS OF IMPATIENS AND LEAVES OF PANDANUS, IN DRIED AND LIQUID FORM, A METHOD OF ITS OBTAINING AND USE THEREOF PBCLABS Sp. z o.o. (PL) 2024-06-05 — — EP claimed
CN-117517485-A Liquid chromatography-mass spectrometry analysis method and application of safflower preparation 神威药业集团有限公司 2024-02-06 — — CN claimed
CN-116869112-A Method for simultaneously improving content of seven flavonol glycosides in peaches 浙江大学山东(临沂)现代农业研究院 2023-10-13 — — CN claimed
CN-116855466-A Flavonoid rutinoside biosynthesis related 1,6 rhamnosyl transferase and application thereof 浙江大学 2023-10-10 — — CN claimed
CN-116242929-A Method for simultaneously measuring 9 components in safflower pharmaceutical composition 神威药业集团有限公司 2023-06-09 — — CN claimed
CN-115769893-A Polyphenol additive capable of reducing glycemic index of food and application thereof 中南林业科技大学 2023-03-10 — — CN claimed
CN-115144485-A Characteristic fingerprint spectrum of traditional Chinese medicine composition for treating chronic recurrent eczema and content determination and quality control method 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） 2022-10-04 — — CN claimed
CN-112043746-A Salvia miltiorrhiza stem and leaf effective part with effect of improving microcirculation disturbance and preparation and application thereof 南京中医药大学 2020-12-08 — — CN claimed
CN-111721857-A Method for identifying litchi varieties by using extensive targeted metabonomics technology 广东省农业科学院果树研究所 2020-09-29 — — CN claimed
US-20190127812-A1 Inhibition of Sucrose Crystallization Using Glycosides PURDUE RESEARCH FOUNDATION (US) 2019-05-02 — — US claimed
WO-2016157233-A1 PRUNUS SPINOSA EXTRACTS WITH ANTI-TUMOR ACTIVITY Istituto Superiore di Sanità (IT) 2016-10-06 — — WO claimed
WO-2013067543-A1 METHODS AND COMPOSITIONS FOR ADMINISTERING A SPECIFIC WAVELENGTH PHOTOTHERAPY FOLLEA INTERNATIONAL LTD. (CN) 2013-05-10 — — WO claimed
US-20130115180-A1 Methods And Compositions For Administering A Specific Wavelength Phototherapy APPLIED BIOLOGY, INC. 2013-05-09 — — US claimed
WO-2006001665-A1 COMPOSITION FOR PREVENTING OR TREATING ACUTE OR CHRONIC DEGENERATIVE BRAIN DISEASES INCLUDING FLAVONOID DERIVATIVES SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) 2006-01-05 — — WO claimed
EP-4378448-B1 EXTRACT OF FLOWERS, LEAVES AND/OR SEED PODS OF IMPATIENS AND LEAVES OF PANDANUS, IN DRIED AND LIQUID FORM, A METHOD OF ITS OBTAINING AND USE THEREOF PBCLABS SP Z O O (PL) 2026-05-20 — — EP disclosed
EP-1098631-A1 PHARMACEUTICAL COMPOSITION IN PARTICULAR FOR PREVENTING AND TREATING MUCOSITIS INDUCED BY RADIOTHERAPY OR CHEMOTHERAPY LABORATOIRE L. LAFON (FR) 2001-05-16 — — EP disclosed
WO-2000004878-A1 PHARMACEUTICAL COMPOSITION IN PARTICULAR FOR PREVENTING AND TREATING MUCOSITIS INDUCED BY RADIOTHERAPY OR CHEMOTHERAPY LABORATOIRE L. LAFON (FR) 2000-02-03 — — WO disclosed