Nicotifloroside

Nicotifloroside

SCHEMBL29403154

C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(-c4ccc(O)cc4)oc4cc(O)cc(O)c4c3=O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HB P07237 6/20 1.00
XDH P47989 2/20 1.00
POLB P06746 2/20 1.00
GAA P10253 2/20 1.00
APEX1 P27695 1/20 1.00
RECQL P46063 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
KDM4E B2RXH2 4/20 0.88
MAPT P10636 3/20 0.88
HES1 Q14469 2/20 0.88
FANCF Q9NPI8 2/20 0.88
ACHE P22303 2/20 0.88
KDM1A O60341 1/20 0.88
PRSS1 P07477 1/20 0.88
PRSS2 P07478 1/20 0.88
ADRA2A P08913 1/20 0.88
HMGB1 P09429 1/20 0.88
CFTR P13569 1/20 0.88
ADRA2C P18825 1/20 0.88
MAOA P21397 1/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Kaempferol-3-O-Rutinoside SCHEMBL14916541 1.00 P4HB (1.00) P4HBXDHPOLBGAAAPEX1
Nicotifloroside SCHEMBL240355 1.00 P4HB (1.00) P4HBXDHPOLBGAAAPEX1
Kaempferol-3-O-Rutinoside SCHEMBL21013016 1.00 P4HB (1.00) P4HBXDHPOLBGAAAPEX1
Kaempferol-3-O-Rutinoside SCHEMBL15591885 1.00 P4HB (1.00) P4HBXDHPOLBGAAAPEX1
Kaempferol-3-O-Rutinoside SCHEMBL10000318 1.00 P4HB (1.00) P4HBXDHPOLBGAAAPEX1
Kaempferol-3-O-Rutinoside SCHEMBL29522866 1.00 P4HB (1.00) P4HBXDHPOLBGAAAPEX1
Kaempferol-3-O-Rutinoside SCHEMBL31720528 1.00 P4HB (1.00) P4HBXDHPOLBGAAAPEX1
SCHEMBL22678450 0.94 P4HB (0.89) P4HBXDHPOLBGAAAPEX1
SCHEMBL7591453 0.94 P4HB (0.89) P4HBXDHPOLBGAAAPEX1
SCHEMBL7591460 0.94 P4HB (0.89) P4HBXDHPOLBGAAAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091075-A1 METHOD FOR IMPROVING SKIN CONDITION AND/OR RELIEVING ANEMIA BY PEACH EXTRACT TCI CO LTD (TW) 2026-04-02 US claimed
WO-2025202485-A1 COMPOSITION COMPRISING TROPAEOLUM MAJUS AND ARMORACIA RUSTICANA REPHA GMBH BIOLOGISCHE ARZNEIMITTEL (DE) 2025-10-02 WO claimed
WO-2025024478-A1 COMPOSITIONS FOR THE MODULATION OF TASTE IXORA SCIENTIFIC INC. (US) 2025-01-30 WO claimed
CN-117752669-A Application of phenolic compound in preparation of antidepressant drugs 华南农业大学 2024-03-26 CN claimed
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 WO claimed
CN-114588173-B Application of nicotiflorin or its analogue in preparing medicine for preventing and treating traumatic brain injury 中国人民解放军海军军医大学 2023-08-22 CN claimed
EP-4153204-A1 DRUG DELIVERY SYSTEM BASED ON CALCIUM PHOSPHATE NANOPARTICLES FUNCTIONALIZED WITH BIOACTIVE COMPOUNDS FROM EUPHORBIA EXTRACT AND THE USES THEREOF Cellbitec, S.L. (ES) 2023-03-29 EP claimed
WO-2023038480-A1 COMPOSITION, FOR PREVENTING, TREATING OR RELIEVING INFLUENZA VIRUS INFECTION, COMPRISING MIXTURE OF AGRIMONIA PILOSA EXTRACT AND GALLA RHOIS EXTRACT AS ACTIVE INGREDIENT 에이피알지 주식회사 2023-03-16 WO claimed
EP-3485870-B1 STABILISING COSMETIC COMPOSITION FOR REDUCING THE DEGRADATION OF UNSTABLE COSMETIC ACTIVE INGREDIENTS THOREL JEAN NOEL (FR) 2023-03-08 EP claimed
CN-109956984-B Method for extracting and separating nicotiflorin from China rose 河南大学 2022-01-28 CN claimed
WO-2026104886-A1 METHOD FOR EXTRACTING LOW-MOLECULAR WEIGHT COLLAGEN USING POLLACK SKIN, LOW-MOLECULAR WEIGHT COLLAGEN, AND COSMETIC COMPOSITION COMPRISING SAME WITH SKIN REGENERATION EFFICACY 유엔케이코리아 주식회사 2026-05-21 WO disclosed
CN-122055354-A Lipid compounds and related compositions and uses 波西达治疗公司 2026-05-15 CN disclosed
US-20260101926-A1 VAPORIZING DEVICE MINSKOFF NOAH MARK (US) 2026-04-16 US disclosed
US-20260091075-A1 METHOD FOR IMPROVING SKIN CONDITION AND/OR RELIEVING ANEMIA BY PEACH EXTRACT TCI CO LTD (TW) 2026-04-02 US disclosed
EP-4702038-A1 METHOD OF PRODUCING POLYPHENOLS Nicoventures Trading Limited (GB) 2026-03-04 EP disclosed
US-20220054409-A1 RAPIDLY-ORODISPERSIBLE TABLETS HAVING AN INTERIOR CAVITY Aprecia Pharmaceuticals LLC 2022-02-24 US disclosed
CN-113995776-A Ginkgo leaf flavone extract, preparation method thereof and characteristic map construction method 浙江康恩贝制药股份有限公司 2022-02-01 CN disclosed
CN-109956984-B Method for extracting and separating nicotiflorin from China rose 河南大学 2022-01-28 CN disclosed
CN-109956984-B Method for extracting and separating nicotiflorin from China rose 河南大学 2022-01-28 CN disclosed
CN-109956984-B Method for extracting and separating nicotiflorin from China rose 河南大学 2022-01-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260101926-A1 VAPORIZING DEVICE SARAF, HSF1, TFPI P4HB 714/4885XDH 3756/4885POLB 2174/4885
US-20260091075-A1 METHOD FOR IMPROVING SKIN CONDITION AND/OR RELIEVING ANEMIA BY PEACH EXTRACT ARG2, FECH, COX5B P4HB 2146/4885XDH 3170/4885POLB 1957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.