Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 6/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24035200 | 0.81 | CYP2D6 (0.40) | MAPTCNR2TP53ALDH1A1TSHR | |
| SCHEMBL24035888 | 0.78 | MAPT (0.38) | MAPTTP53ALDH1A1TSHRLMNA | |
| SCHEMBL24035933 | 0.77 | MAPT (0.39) | MAPTTP53ALDH1A1LMNAKMT2A | |
| SCHEMBL30177510 | 0.76 | ALDH1A1 (0.37) | MAPTCNR2TP53ALDH1A1TSHR | |
| SCHEMBL24852937 | 0.75 | CNR2 (0.34) | MAPTCNR2TP53ALDH1A1TSHR | |
| SCHEMBL26735402 | 0.75 | MAPT (0.39) | MAPTTP53KMT2A | |
| SCHEMBL24035276 | 0.73 | CNR2 (0.35) | MAPTCNR2TP53ALDH1A1 | |
| SCHEMBL24036353 | 0.73 | ACACB (0.39) | MAPTCNR2TP53MEN1LMNA | |
| SCHEMBL26627925 | 0.73 | MAPT (0.38) | MAPTCNR2TP53ALDH1A1LMNA | |
| SCHEMBL30295615 | 0.72 | CNR1 (0.36) | MAPTALDH1A1TSHRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231474-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2021-11-18 | — | — | WO | disclosed |