Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269005 | 0.85 | NPC1 (0.61) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL16641094 | 0.83 | CYP19A1 (0.77) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL31157848 | 0.83 | CYP19A1 (0.77) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL3579994 | 0.83 | ALOX5 (0.66) | ATMKDM4ECA2POLBCYP1A2 | |
| SCHEMBL10899432 | 0.82 | CA2 (0.57) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL11265688 | 0.81 | MAPT (0.61) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL28176844 | 0.81 | KDM4E (0.62) | ATMKDM4ECA2CYP19A1AOC3 | |
| SCHEMBL347209 | 0.81 | FFAR4 (0.61) | ATMKDM4ECA2KMT2AMEN1 | |
| SCHEMBL1032004 | 0.81 | KDM4E (0.62) | ATMKDM4ECA2CYP19A1AOC3 | |
| SCHEMBL1302702 | 0.81 | KMT2A (0.64) | ATMKDM4ECA2POLBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
| US-6218424-B1 | FOR EFFECTING NEURONAL ACTIVITIES IN ANIMALS, INCLUDING TREATING NEUROLOGICAL DISORDERS | GPI NIL HOLDINGS, INC. | 2001-04-17 | — | — | US | disclosed |
| CN-1020607-C | PROCESS FOR PREPARATION OF BENZOTHIAZINE DERIVS. | HOECHST AG (DE) | 1993-05-12 | — | — | CN | disclosed |
| CN-85101312-A | Process for preparing Benzothiazine derivatives | — | 1987-04-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | HCRTR2, HCRTR1, HRH3 | ATM 4794/4885KDM4E 452/4885CA2 985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.