SCHEMBL24037352

SCHEMBL24037352

c1ccc2cc(-c3nccc4ccsc34)ccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 1/20 0.46
HTR5A P47898 1/20 0.46
MAPK9 P45984 2/20 0.42
MAPK10 P53779 2/20 0.42
MAPK8 P45983 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
ALDH1A1 P00352 2/20 0.41
AR P10275 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
NFKB1 P19838 1/20 0.41
GFER P55789 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
SIRT2 Q8IXJ6 1/20 0.40
CYP1A2 P05177 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14001968 0.82 PDPK1 (0.46) HTR2BHTR5ASMN1; SMN2NPC1RAB9A
SCHEMBL16866588 0.77 HTR2B (0.48) HTR2BHTR5AMAPK9MAPK10MAPK8
SCHEMBL24037353 0.76 HTR2B (0.44) HTR2BHTR5AMAPK9MAPK10MAPK8
SCHEMBL8016628 0.76 PDE3B (0.39) SMN1; SMN2NPC1RAB9AALDH1A1KDM4E
SCHEMBL729774 0.75 HTR2B (0.59) HTR2BHTR5AMAPK9MAPK10MAPK8
SCHEMBL29445836 0.75 HTR2B (0.59) HTR2BHTR5AMAPK9MAPK10MAPK8
SCHEMBL18222854 0.74 SRC (0.38) SMN1; SMN2NPC1RAB9AADORA2AADORA1
SCHEMBL29823704 0.74 SRC (0.38) SMN1; SMN2NPC1RAB9AADORA2AADORA1
SCHEMBL572750 0.71 PDPK1 (0.60) SMN1; SMN2NPC1RAB9AALDH1A1AR
SCHEMBL24037349 0.71 HTR2B (0.40) HTR2BHTR5AMAPK9MAPK10MAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210355148-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210355148-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CYBA, C1S, CYC1 HTR2B 2538/4885HTR5A 4334/4885MAPK9 3063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.