Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8016628 | 0.82 | PDE3B (0.39) | KDM4ENPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL24037352 | 0.82 | HTR2B (0.46) | KDM4ENPC1RAB9AMAPTKMT2A | |
| SCHEMBL24795600 | 0.78 | PDPK1 (0.40) | PDPK1KDM4ENPC1RAB9AL3MBTL1 | |
| SCHEMBL18222854 | 0.77 | SRC (0.38) | NPC1RAB9AADORA3ADORA1ADORA2A | |
| SCHEMBL29823704 | 0.77 | SRC (0.38) | NPC1RAB9AADORA3ADORA1ADORA2A | |
| SCHEMBL23503946 | 0.76 | SCN9A (0.46) | KDM4ENPC1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL30460682 | 0.73 | MAPT (0.37) | PDPK1KDM4EMAPTKMT2AATR | |
| SCHEMBL3761424 | 0.73 | NPC1 (0.50) | KDM4ENPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL23170962 | 0.71 | CYP2A6 (0.42) | KDM4ENPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL2576162 | 0.70 | PDPK1 (0.46) | PDPK1KDM4ENPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402877-A1 | ELECTROLUMINESCENT DEVICE | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2022-12-22 | — | — | US | disclosed |
| US-11325932-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2022-05-10 | — | — | US | disclosed |
| US-20200283462-A1 | Organic Electroluminescent Materials and Devices | UNIVERSAL DISPLAY CORPORATION, | 2020-09-10 | — | — | US | disclosed |
| US-10183013-B2 | Cyclic sulfonamide containing derivatives as inhibitors of hedgehog signaling pathway | NANT HOLDINGS IP, LLC (US) | 2019-01-22 | — | — | US | disclosed |
| US-20170135992-A1 | CYCLIC SULFONAMIDE CONTAINING DERIVATIVES AS INHIBITORS OF HEDGEHOG SIGNALING PATHWAY | NANT HOLDINGS IP, LLC | 2017-05-18 | — | — | US | disclosed |
| US-20170135992-A1 | CYCLIC SULFONAMIDE CONTAINING DERIVATIVES AS INHIBITORS OF HEDGEHOG SIGNALING PATHWAY | NANT HOLDINGS IP, LLC | 2017-05-18 | — | — | US | disclosed |
| US-9499539-B2 | Cyclic sulfonamide containing derivatives as inhibitors of hedgehog signaling pathway | NANTBIOSCIENCE, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-20150299190-A1 | CYCLIC SULFONAMIDE CONTAINING DERIVATIVES AS INHIBITORS OF HEDGEHOG SIGNALING PATHWAY | NANT HOLDINGS IP, LLC | 2015-10-22 | — | — | US | disclosed |
| US-7445857-B2 | Organometallic complex and organic electroluminescent devices utilizing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2008-11-04 | — | — | US | disclosed |
| US-7445857-B2 | Organometallic complex and organic electroluminescent devices utilizing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2008-11-04 | — | — | US | disclosed |
| US-20070237981-A1 | Organometallic complex and organic electroluminescent devices utilizing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE | 2007-10-11 | — | — | US | disclosed |
| US-20070237981-A1 | Organometallic complex and organic electroluminescent devices utilizing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10183013-B2 | Cyclic sulfonamide containing derivatives as inhibitors of hedgehog signaling pathway | SMO, SHH, SOS1 | PDPK1 715/4885KDM4E 2841/4885NPC1 3665/4885 |
| US-20220402877-A1 | ELECTROLUMINESCENT DEVICE | MCOLN2, MCOLN1, LDHB | PDPK1 3852/4885KDM4E 1211/4885NPC1 2599/4885 |
| US-20200283462-A1 | Organic Electroluminescent Materials and Devices | L1CAM, KCNN4, ITGB4 | PDPK1 4267/4885KDM4E 1634/4885NPC1 2504/4885 |
| US-20150299190-A1 | CYCLIC SULFONAMIDE CONTAINING DERIVATIVES AS INHIBITORS OF HEDGEHOG SIGNALING PATHWAY | SMO, SHH, SOS1 | PDPK1 715/4885KDM4E 2841/4885NPC1 3665/4885 |
| US-20170135992-A1 | CYCLIC SULFONAMIDE CONTAINING DERIVATIVES AS INHIBITORS OF HEDGEHOG SIGNALING PATHWAY | SMO, SHH, SOS1 | PDPK1 715/4885KDM4E 2841/4885NPC1 3665/4885 |
| US-11325932-B2 | Organic electroluminescent materials and devices | L1CAM, RTN4, KCNN4 | PDPK1 4467/4885KDM4E 2017/4885NPC1 3444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.