Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709616 | 0.91 | — | — | |
| SCHEMBL4094372 | 0.88 | TDP1 (0.56) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| Hydrochloric Acid SCHEMBL31628644 | 0.85 | TDP1 (0.53) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| Formaldehyde SCHEMBL27536836 | 0.83 | MAPT (0.48) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| SCHEMBL351125 | 0.80 | MAPT (0.67) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| SCHEMBL9518383 | 0.80 | MAPT (0.67) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| SCHEMBL6301188 | 0.80 | MAPT (0.67) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| SCHEMBL2024128 | 0.78 | CYP3A4 (1.00) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| SCHEMBL258287 | 0.78 | CYP3A4 (1.00) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| Benzidine SCHEMBL29021 | 0.78 | CYP3A4 (1.00) | CYP3A4TDP1ALDH1A1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9603971-B2 | Silk-based ionomeric compositions | TRUSTEES OF TUFTS COLLEGE (US) | 2017-03-28 | — | — | US | disclosed |
| US-20130039986-A1 | Silk-Based Ionomeric Compositions | TRUSTEES OF TUFTS COLLEGE (US) | 2013-02-14 | — | — | US | disclosed |
| WO-2011109691-A2 | SILK-BASED IONOMERIC COMPOSITIONS | TRUSTEES OF TUFTS COLLEGE (US) | 2011-09-09 | — | — | WO | disclosed |