SCHEMBL6301188

SCHEMBL6301188

Nc1ccc(-c2ccc(Nc3ccc(-c4ccc(Nc5ccc(-c6ccc(N)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.67
ALDH1A1 P00352 5/20 0.67
CYP3A4 P08684 3/20 0.67
L3MBTL1 Q9Y468 3/20 0.67
ALOX12 P18054 2/20 0.67
CYP1A2 P05177 1/20 0.67
CYP2C9 P11712 1/20 0.67
CYP2C19 P33261 1/20 0.67
HTT P42858 1/20 0.67
TDP1 Q9NUW8 4/20 0.65
TP53 P04637 3/20 0.65
RAD52 P43351 1/20 0.61
NR4A1 P22736 1/20 0.56
HSD17B10 Q99714 4/20 0.52
TAAR1 Q96RJ0 1/20 0.52
KDM4E B2RXH2 3/20 0.50
ALOX15 P16050 2/20 0.50
HPGD P15428 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
APP P05067 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL351125 1.00 MAPT (0.67) MAPTALDH1A1CYP3A4L3MBTL1ALOX12
SCHEMBL9518383 1.00 MAPT (0.67) MAPTALDH1A1CYP3A4L3MBTL1ALOX12
SCHEMBL5428343 0.91 MAPT (0.78) MAPTALDH1A1CYP3A4L3MBTL1ALOX12
SCHEMBL5438258 0.91 MAPT (0.78) MAPTALDH1A1CYP3A4L3MBTL1ALOX12
SCHEMBL12747008 0.91 MAPT (0.78) MAPTALDH1A1CYP3A4L3MBTL1ALOX12
SCHEMBL18289620 0.91 MAPT (0.78) MAPTALDH1A1CYP3A4L3MBTL1ALOX12
SCHEMBL33864 0.91 MAPT (0.78) MAPTALDH1A1CYP3A4L3MBTL1ALOX12
SCHEMBL2478605 0.90 MAPT (0.86) MAPTALDH1A1CYP3A4L3MBTL1ALOX12
SCHEMBL7007688 0.90 MAPT (0.86) MAPTALDH1A1CYP3A4L3MBTL1ALOX12
SCHEMBL5803919 0.90 MAPT (0.77) MAPTALDH1A1CYP3A4L3MBTL1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6927537-B2 Organic electroluminescence device OPTREX CORPORATION (JP) 2005-08-09 US disclosed
US-20040191565-A1 Organic electroluminescence device OPTREX CORPORATION (JP) 2004-09-30 US disclosed