Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22268864 | 0.88 | ACE2 (0.42) | TSHRLMNAACE2OPRM1 | |
| SCHEMBL896202 | 0.82 | — | — | |
| SCHEMBL4276528 | 0.82 | OPRM1 (0.48) | TSHRLMNAACE2OPRM1 | |
| SCHEMBL4271949 | 0.80 | ACE2 (0.48) | TSHRLMNAACE2OPRM1 | |
| SCHEMBL671306 | 0.80 | ACE2 (0.48) | TSHRLMNAACE2OPRM1 | |
| SCHEMBL4275345 | 0.80 | ACE2 (0.48) | TSHRLMNAACE2OPRM1 | |
| SCHEMBL10480702 | 0.80 | ACE2 (0.48) | TSHRLMNAACE2OPRM1 | |
| SCHEMBL4279140 | 0.79 | TSHR (0.46) | TSHRLMNAACE2OPRM1 | |
| SCHEMBL18583773 | 0.79 | LMNA (0.39) | TSHRLMNAACE2OPRM1 | |
| SCHEMBL4269680 | 0.79 | TSHR (0.56) | TSHROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021229302-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2021-11-18 | — | — | WO | disclosed |