SCHEMBL2405018

SCHEMBL2405018

Nc1ccc2c(c1)C(C(=O)O)C(=O)C=C2

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.33
ALDH1A1 P00352 4/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
KDM4E B2RXH2 3/20 0.33
THRB P10828 2/20 0.33
RECQL P46063 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP3A4 P08684 2/20 0.33
USP2 O75604 1/20 0.33
POLB P06746 1/20 0.33
PKM P14618 1/20 0.33
APEX1 P27695 1/20 0.33
BLM P54132 1/20 0.33
MCL1 Q07820 1/20 0.33
TNF P01375 1/20 0.33
HSPD1 P10809 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL129881 0.75 CYP2D6 (0.44) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL940449 0.71 ALDH1A1 (0.39) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL998511 0.70 EDNRB (0.44) MEN1KMT2AKDM4ETDP1POLB
SCHEMBL1225882 0.69 MEN1 (0.31) MAPTMEN1KMT2ATHRBALOX15
SCHEMBL2411278 0.67 MMP2 (0.33) MAPTGAACYP2D6
SCHEMBL16678891 0.66 BRD4 (0.46) KMT2APKM
SCHEMBL2403993 0.62 ALDH1A1 (0.33) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL8797292 0.62 HTR2A (0.43) ALDH1A1KDM4EPOLBCYP2C9CYP2D6
SCHEMBL13676237 0.61 HTR6 (0.37) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL27971847 0.61 ALDH1A1 (0.38) MAPTALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed