SCHEMBL2404075

SCHEMBL2404075

NOc1cccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL251357 0.77 MGMT (0.40)
SCHEMBL4082360 0.77 FBP1 (0.39)
SCHEMBL30039658 0.76 FBP1 (0.40)
SCHEMBL10497238 0.76 FBP1 (0.35)
SCHEMBL9682640 0.74 MGMT (0.39)
SCHEMBL10638201 0.74
SCHEMBL266567 0.72
SCHEMBL181927 0.72
SCHEMBL247102 0.72
SCHEMBL73652 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240148777-A1 METHODS AND COMPOSITIONS FOR TREATING CLOSTRIDIODES DIFFICILE INFECTIONS MATRIVAX INC (US) 2024-05-09 US disclosed
EP-4313065-A2 METHODS AND COMPOSITIONS FOR TREATING CLOSTRIDIODES DIFFICILE INFECTIONS Matrivax, Inc. (US) 2024-02-07 EP disclosed
CN-117460516-A Methods and compositions for treating clostridium difficile infection 马特里瓦克斯公司 2024-01-26 CN disclosed
US-20210401960-A1 MULTIVALENT GLYCOCONJUGATES IMMUNOGENIC COMPOSITIONS BHARAT BIOTECH INTERNATIONAL LIMITED (IN) 2021-12-30 US disclosed
EP-3876981-A1 MULTIVALENT GLYCOCONJUGATES IMMUNOGENIC COMPOSITIONS Bharat Biotech International Limited (IN) 2021-09-15 EP disclosed
CN-113271967-A Multivalent glycoconjugate immunogenic compositions 巴拉特生物技术国际有限公司 2021-08-17 CN disclosed
CN-107748157-B Respiration detection system based on chemically modified surface enhanced Raman scattering chip 中国科学院微电子研究所 2020-08-04 CN disclosed
US-9144604-B2 Vaccine for Shigella THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2015-09-29 US disclosed
US-20140378669-A1 METHODS FOR CONJUGATION OF OLIGOSACCHARIDES OR POLYSACCHARIDES TO PROTEIN CARRIERS THROUGH OXIME LINKAGES VIA 3-DEOXY-D-MANNO-OCTULSONIC ACID The U.S.A , as represented by the Secretary, Department of Health and Human Services (US) 2014-12-25 US disclosed
US-20140242666-A1 VACCINE FOR SHIGELLA The United States of America, as represented by the Secretary, Department of Health and Human Ser (US) 2014-08-28 US disclosed
US-8795680-B2 Methods for conjugation of oligosaccharides or polysaccharides to protein carriers through oxime linkages via 3-deoxy-D-manno-octulsonic acid THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2014-08-05 US disclosed
US-8747863-B2 Vaccine for shigella THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2014-06-10 US disclosed
WO-2012106251-A2 PERTUSSIS VACCINE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2012-08-09 WO disclosed
US-20110212125-A1 VACCINE FOR SHIGELLA NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2011-09-01 US disclosed
US-20100158937-A1 METHODS FOR CONJUGATION OF OLIGOSACCHARIDES OR POLYSACCHARIDES TO PROTEIN CARRIERS THROUGH OXIME LINKAGES VIA 3-DEOXY-D-MANNO-OCTULSONIC ACID UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE 2010-06-24 US disclosed
WO-2010019890-A2 VACCINE FOR SHIGELLA THE GOVERNMENT OF THE USA, AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICES (US) 2010-02-18 WO disclosed
WO-2008013735-A2 METHODS FOR CONJUGATION OF OLIGOSACCHARIDES OR POLYSACCHARIDES TO PROTEIN CARRIERS THROUGH OXIME LINKAGES VIA 3-DEOXY-D-MANNO-OCTULSONIC ACID THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2008-01-31 WO disclosed
US-4647698-A Novel compositions SANDOZ LTD. (US) 1987-03-03 US disclosed