⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4082360 | 0.77 | FBP1 (0.39) | — | |
| SCHEMBL251357 | 0.77 | MGMT (0.40) | — | |
| SCHEMBL9682640 | 0.74 | MGMT (0.39) | — | |
| SCHEMBL73652 | 0.72 | — | — | |
| SCHEMBL8965381 | 0.72 | — | — | |
| SCHEMBL16553362 | 0.72 | — | — | |
| SCHEMBL266567 | 0.72 | — | — | |
| SCHEMBL181927 | 0.72 | — | — | |
| SCHEMBL2404075 | 0.72 | — | — | |
| SCHEMBL245814 | 0.72 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473486-B2 | PYRIMIDINES AS HEPCIDINE ANTAGONISTS | VIFOR INT AG (CH) | 2021-09-22 | — | — | EP | disclosed |
| US-20190047968-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | FMC CORP (US) | 2019-02-14 | — | — | US | disclosed |
| US-10081608-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | FMC CORPORATION (US) | 2018-09-25 | — | — | US | disclosed |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-05-11 | — | — | US | disclosed |
| US-9573909-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | FMC CORPORATION (US) | 2017-02-21 | — | — | US | disclosed |
| EP-2675526-B1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2017-02-01 | — | — | EP | disclosed |
| EP-3020709-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | FMC CORPORATION (US) | 2016-05-18 | — | — | EP | disclosed |
| EP-2542538-B1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | FMC CORP (US) | 2015-12-30 | — | — | EP | disclosed |
| EP-2473486-B1 | PYRIMIDINES AS HEPCIDINE ANTAGONISTS | VIFOR INT AG (CH) | 2015-10-28 | — | — | EP | disclosed |
| US-9102688-B2 | Sulfonaminoquinoline hepcidin antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2015-08-11 | — | — | US | disclosed |
| EP-0055851-A1 | 11-Deoxy-hetero-imino-prostacyclins, processes for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-07-14 | — | — | EP | disclosed |
| US-4312882-A | ANTICOAGULANTS, HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-26 | — | — | US | disclosed |
| US-4304783-A | ANTITHROMBOTIC, ANTIINFARCT, HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-12-08 | — | — | US | disclosed |
| US-4296121-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-10-20 | — | — | US | disclosed |
| EP-0034778-A1 | Hetero-imino-prostacyclins and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-09-02 | — | — | EP | disclosed |
| EP-0029527-A2 | Prostaglandin derivatives of the 6-keto-PGA1 series, process for their production as well as their use in medicaments and their intermediate products | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-03 | — | — | EP | disclosed |
| EP-0019069-A2 | 6-Keto PGE1 compounds, their preparation and therapeutic application, PGI1 compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-11-26 | — | — | EP | disclosed |
| EP-0013955-A1 | Analogues of prostacyclin, their intermediates, a process for their preparation and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-08-06 | — | — | EP | disclosed |
| EP-0008077-A2 | Prostaglandin derivatives with a delta-2-PGF2 structure or a delta-2-PGE2 structure, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-02-20 | — | — | EP | disclosed |
| US-3957771-A | PHOSPHINIC ACID CHLORIDES, ALCOHOLS, HYDROLYSIS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |