Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.63 |
| ▸ | LTA4H | P09960 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24041743 | 0.92 | HTT (0.76) | HTTLTA4HL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL24041863 | 0.89 | HTT (0.62) | HTTLTA4HL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL24041777 | 0.89 | HTT (0.62) | HTTLTA4HL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL24041750 | 0.88 | L3MBTL1 (0.74) | HTTLTA4HL3MBTL1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL30457596 | 0.88 | HTT (0.60) | HTTLTA4HL3MBTL1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL29006865 | 0.88 | HTT (0.60) | HTTLTA4HL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL24041766 | 0.87 | SMN1; SMN2 (0.72) | HTTLTA4HL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL24041805 | 0.86 | HTT (0.74) | HTTLTA4HL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL24041832 | 0.83 | LTA4H (0.56) | HTTLTA4HL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL24041782 | 0.82 | HTT (0.60) | HTTLTA4HL3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021233994-A1 | SOCE INHIBITORS AND THERAPEUTIC USES THEREOF | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2021-11-25 | — | — | WO | disclosed |
| EP-3912972-A1 | SOCE INHIBITORS AND THERAPEUTIC USES THEREOF | Centre Hospitalier Régional et Universitaire de Brest (FR) | 2021-11-24 | — | — | EP | disclosed |