Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | IGF1R | P08069 | 2/20 | 0.39 |
| ▸ | FLT4 | P35916 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29006858 | 0.99 | PKM (0.42) | PKMLTA4HHTTPRPS1KMT2A | |
| Hydrochloric Acid SCHEMBL30457528 | 0.99 | PKM (0.42) | PKMLTA4HHTTPRPS1KMT2A | |
| SCHEMBL24041741 | 0.91 | PKM (0.50) | PKMHTTPRPS1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL30457744 | 0.89 | PKM (0.49) | PKMHTTPRPS1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL29006843 | 0.89 | PKM (0.49) | PKMHTTPRPS1KMT2AMAPT | |
| SCHEMBL24041837 | 0.89 | KDM4E (0.47) | PKMLTA4HHTTKMT2ASMN1; SMN2 | |
| SCHEMBL24041777 | 0.83 | HTT (0.62) | LTA4HHTTKMT2AL3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30457596 | 0.82 | HTT (0.60) | LTA4HHTTKMT2AL3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29006865 | 0.82 | HTT (0.60) | LTA4HHTTKMT2AL3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29006860 | 0.82 | PKM (0.39) | PKMHTTPRPS1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021233994-A1 | SOCE INHIBITORS AND THERAPEUTIC USES THEREOF | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2021-11-25 | — | — | WO | disclosed |
| EP-3912972-A1 | SOCE INHIBITORS AND THERAPEUTIC USES THEREOF | Centre Hospitalier Régional et Universitaire de Brest (FR) | 2021-11-24 | — | — | EP | disclosed |