Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.39 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30457744 | 0.99 | PKM (0.49) | PKMHTTPRPS1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL29006843 | 0.99 | PKM (0.49) | PKMHTTPRPS1KMT2AMAPT | |
| SCHEMBL24041847 | 0.91 | PKM (0.43) | PKMHTTPRPS1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL30457528 | 0.89 | PKM (0.42) | PKMHTTPRPS1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL29006858 | 0.89 | PKM (0.42) | PKMHTTPRPS1KMT2AMAPT | |
| SCHEMBL24041738 | 0.86 | MET (0.53) | HTTQPCTQPCTLMETHDAC1 | |
| Hydrochloric Acid SCHEMBL29006860 | 0.84 | PKM (0.39) | PKMHTTPRPS1KMT2AMAPT | |
| SCHEMBL11313566 | 0.80 | HTT (0.77) | PKMHTTTDP1 | |
| Hydrochloric Acid SCHEMBL29006871 | 0.78 | HTT (0.74) | PKMHTTALPLALPGTDP1 | |
| Hydrochloric Acid SCHEMBL30341872 | 0.78 | HTT (0.74) | PKMHTTALPLALPGTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021233994-A1 | SOCE INHIBITORS AND THERAPEUTIC USES THEREOF | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2021-11-25 | — | — | WO | disclosed |
| EP-3912972-A1 | SOCE INHIBITORS AND THERAPEUTIC USES THEREOF | Centre Hospitalier Régional et Universitaire de Brest (FR) | 2021-11-24 | — | — | EP | disclosed |