Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TK1 | P04183 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | TK2 | O00142 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311498 | 1.00 | LMNA (0.60) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL20131193 | 1.00 | LMNA (0.60) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL12111185 | 1.00 | LMNA (0.60) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL19944089 | 1.00 | LMNA (0.60) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL1311495 | 1.00 | LMNA (0.60) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL12112419 | 1.00 | LMNA (0.60) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL15491233 | 0.91 | TK1 (0.55) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL15066132 | 0.91 | TK1 (0.57) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL18873431 | 0.91 | TK1 (0.57) | LMNASMN1; SMN2TK1ALOX12ADRA1A | |
| SCHEMBL17283457 | 0.91 | TK1 (0.57) | LMNASMN1; SMN2TK1ALOX12ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345915-B1 | 5-POSITION MODIFIED PYRIMIDINES AND THEIR USE | SOMALOGIC INC (US) | 2021-11-24 | — | — | EP | disclosed |