Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 5/20 | 0.41 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.41 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103461 | 1.00 | GPBAR1 (0.42) | GPBAR1CCR5TRPC3TRPC6RAB9A | |
| SCHEMBL22043704 | 1.00 | GPBAR1 (0.42) | GPBAR1CCR5TRPC3TRPC6RAB9A | |
| SCHEMBL17805416 | 0.99 | GPBAR1 (0.41) | GPBAR1CCR5TRPC3TRPC6RAB9A | |
| SCHEMBL24016955 | 0.99 | RAB9A (0.41) | GPBAR1CCR5TRPC3TRPC6RAB9A | |
| SCHEMBL18532583 | 0.86 | GPBAR1 (0.49) | GPBAR1TRPC3TRPC6PRMT5WDR77 | |
| SCHEMBL17805431 | 0.86 | GPBAR1 (0.49) | GPBAR1TRPC3TRPC6PRMT5WDR77 | |
| SCHEMBL26006171 | 0.85 | PREP (0.46) | GPBAR1PRMT5WDR77CCNCCDK8 | |
| SCHEMBL17805452 | 0.84 | GPBAR1 (0.40) | GPBAR1PRMT5WDR77PREP | |
| SCHEMBL2586526 | 0.83 | CCR5 (0.40) | CCR5KMT2APREPLMNAMAPT | |
| SCHEMBL18532541 | 0.83 | CCR5 (0.40) | CCR5KMT2APREPLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3439658-B1 | SOLUBLE C5AR ANTAGONISTS | CHEMOCENTRYX INC (US) | 2021-11-24 | — | — | EP | disclosed |