SCHEMBL24045752

SCHEMBL24045752

CSc1ccccc1-c1ccc(N2CCCC(NC(=O)Nc3ccc(Cl)nn3)C2=O)c(F)c1

nearest known ligand 0.77

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 16/20 0.77
FPR1 P21462 11/20 0.77
F10 P00742 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18964281 0.87 FPR2 (1.00) FPR2FPR1F10
SCHEMBL30337623 0.87 FPR2 (1.00) FPR2FPR1F10
SCHEMBL24045761 0.83 FPR2 (0.67) FPR2FPR1F10
SCHEMBL24045750 0.81 FPR2 (0.77) FPR2FPR1F10
SCHEMBL4684652 0.80 F10 (0.60) FPR2FPR1F10
SCHEMBL4683375 0.78 FPR2 (0.56) FPR2FPR1F10
SCHEMBL4683093 0.78 F10 (0.57) FPR2FPR1F10
SCHEMBL4680127 0.77 F10 (0.57) FPR2FPR1F10
SCHEMBL30337651 0.76 FPR2 (0.80) FPR2FPR1F10
SCHEMBL18964313 0.76 FPR2 (0.80) FPR2FPR1F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3414227-B1 PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS BRISTOL MYERS SQUIBB CO (US) 2021-11-24 EP disclosed