Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | CRHBP | P24387 | 2/20 | 0.73 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 5/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24045899 | 0.88 | MAPT (0.77) | MAPTCRHBPCRHR2GAASMN1; SMN2 | |
| SCHEMBL24045916 | 0.84 | MAPT (0.82) | MAPTCRHBPCRHR2GAASMN1; SMN2 | |
| SCHEMBL24045901 | 0.84 | MAPT (0.69) | MAPTCRHBPCRHR2GAASMN1; SMN2 | |
| SCHEMBL24045907 | 0.84 | MAPT (0.69) | MAPTCRHBPCRHR2GAASMN1; SMN2 | |
| SCHEMBL28360978 | 0.83 | MME (0.58) | ACEMMECHRM1PDE4AMMP9 | |
| SCHEMBL27785981 | 0.83 | MME (0.61) | MAPTCRHBPCRHR2ACERAB9A | |
| SCHEMBL24045927 | 0.83 | MME (0.61) | MAPTCRHBPCRHR2ACERAB9A | |
| SCHEMBL24045908 | 0.82 | MAPT (0.79) | MAPTCRHBPCRHR2GAASMN1; SMN2 | |
| SCHEMBL4372856 | 0.81 | MAPT (0.76) | MAPTCRHBPCRHR2GAASMN1; SMN2 | |
| SCHEMBL27291251 | 0.81 | MAPT (0.76) | MAPTCRHBPCRHR2GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210361597-A1 | Synthesis of Ibuprofen Hybrid Conjugates as Anti-Inflammatory and Analgesic Agents | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US) | 2021-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210361597-A1 | Synthesis of Ibuprofen Hybrid Conjugates as Anti-Inflammatory and Analgesic Agents | PTGES, DNPEP, PTGES2 | MAPT 1656/4885CRHBP 109/4885CRHR2 749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.